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Gdpd5tm1.1Itl
Targeted Allele Detail
Nomenclature
Symbol: Gdpd5tm1.1Itl
Name: glycerophosphodiester phosphodiesterase domain containing 5; targeted mutation 1.1, inGenious Targeting Laboratory
MGI ID: MGI:5302017
Synonyms: Gde2-
Gene: Gdpd5  Location: Chr7:99381463-99461875 bp, + strand  Genetic Position: Chr7, 54.07 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:178550
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsCre-mediated recombination removed the neo cassette and exon 11. Western blot analysis confirmed the absence of protein expression in the E10.5 spinal cord. (J:178550)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gdpd5 Mutation:  21 strains or lines available
References
Original:  J:178550 Sabharwal P, et al., GDE2 regulates subtype-specific motor neuron generation through inhibition of Notch signaling. Neuron. 2011 Sep 22;71(6):1058-70
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/12/2019
MGI 6.14
The Jackson Laboratory