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Tg(tetO-Ccnd1*T286A,-luc)10897Kuw
Transgene Detail
Nomenclature
Symbol: Tg(tetO-Ccnd1*T286A,-luc)10897Kuw
Name: transgene insertion 10897, Kay-Uwe Wagner
MGI ID: MGI:5300556
Synonyms: TetO-D1
Transgene: Tg(tetO-Ccnd1*T286A,-luc)10897Kuw  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Mutation detailsThe tetracycline operator drives inducible expression of the FLAG-tagged mouse Ccnd1 cDNA with a point mutation that results in the amino acid substitution of alanine for threonine at position 286 (T286A) and an IRES-luciferase. Two lines were generated (10897 and 11233). (J:178842)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:178842 Zhang Q, et al., Cyclin D3 Compensates for the Loss of Cyclin D1 during ErbB2-Induced Mammary Tumor Initiation and Progression. Cancer Res. 2011 Dec 15;71(24):7513-24
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory