Mrs2^{tm1e(KOMP)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Mrs2^{tm1e(KOMP)Wtsi}
• Name: MRS2 magnesium transporter; targeted mutation 1e, Wellcome Trust Sanger Institute
• MGI ID: MGI:5299680
• Gene: Mrs2 Location: Chr13:25171466-25204345 bp, - strand Genetic Position: Chr13, 10.83 cM
• IMPC: Mrs2 gene page

Mutation origin

• Mutant Cell Lines: EPD0016_3_C04, EPD0016_3_D06, EPD0016_3_E04, EPD0016_3_E05, EPD0017_3_E04, EPD0017_3_E05, EPD0017_3_F05, EPD0017_3_G04, EPD0017_3_H06
• Germline Transmission: Unknown
• Parent Cell Line: JM8 (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_st1
• Mutation details: The L1L2_st1 cassette was inserted at position 25203062 of Chromosome 13 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:148605, J:173534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Mrs2 Mutation: 23 strains or lines available

References

• Original: J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009
• All: 2 reference(s)