Htr6tm1(KOMP)Mbp
Targeted Allele Detail
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Symbol: |
Htr6tm1(KOMP)Mbp |
Name: |
5-hydroxytryptamine (serotonin) receptor 6; targeted mutation 1, Mouse Biology Program, UC Davis |
MGI ID: |
MGI:5299467 |
Gene: |
Htr6 Location: Chr4:138788419-138802881 bp, - strand Genetic Position: Chr4, 70.57 cM
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IMPC: |
Htr6 gene page |
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Mutant Cell Lines: |
DEPD00579_4_B01, DEPD00579_4_C01, DEPD00579_4_C04, DEPD00579_4_D01, DEPD00579_4_D03, DEPD00579_4_D04, DEPD00579_4_E02, DEPD00579_4_E03, DEPD00579_4_F02, DEPD00579_4_F03, DEPD00579_4_F04, DEPD00579_4_G03, DEPD00579_4_G04, DEPD00579_4_H02 |
Germline Transmission: |
Unknown
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
KOMP-CSD
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: L1L2_Bact_P
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Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 1349 starting at position 138801311 and ending at position 138802660 of Chromosome 4 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157064)
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Original: |
J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010; |
All: |
1 reference(s) |
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