Arhgap19^m1
Spontaneous Allele Detail

Summary

• Symbol: Arhgap19^m1
• Name: Rho GTPase activating protein 19; mutation 1
• MGI ID: MGI:5297958
• Gene: Arhgap19 Location: Chr19:41755027-41790486 bp, - strand Genetic Position: Chr19, 35.19 cM, cytoband D1
• Alliance: Arhgap19^m1 page

Mutation origin

• Strain of Origin: BALB/cCrl

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: A single T nucleotide insertion is located at position 945 in exon 6 (945T) creating a frameshift mutation resulting in a truncated protein due to a premature stop codon at the end of exon 6 at position 309 (K309*). This mutation is unique to BALB/cCrl and BALB/cAnNCrl strains and is not found in BALB/cJ derived strains. (J:177709)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arhgap19 Mutation: 31 strains or lines available

References

• Original: J:177709 Kooistra MK, et al., Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes. Physiol Genomics. 2012 Jan 18;44(1):35-46
• All: 1 reference(s)