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Map2k7tm1Rjd
Targeted Allele Detail
Summary
Symbol: Map2k7tm1Rjd
Name: mitogen-activated protein kinase kinase 7; targeted mutation 1, Roger J Davis
MGI ID: MGI:5297854
Synonyms: mkk7fl
Gene: Map2k7  Location: Chr8:4288740-4297897 bp, + strand  Genetic Position: Chr8, 1.99 cM, cytoband A1.1
Alliance: Map2k7tm1Rjd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:178060
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    Exons 4-7 were floxed. (J:186492)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Tumor Data
List all tumor models in MMHCdb carrying Map2k7tm1Rjd
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Map2k7 Mutation:  19 strains or lines available
References
Original:  J:178060 Mazzitelli S, et al., The Loss of c-Jun N-Terminal Protein Kinase Activity Prevents the Amyloidogenic Cleavage of Amyloid Precursor Protein and the Formation of Amyloid Plaques In Vivo. J Neurosci. 2011 Nov 23;31(47):16969-76
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory