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Aqp4tm1.1Geno
Targeted Allele Detail
Nomenclature
Symbol: Aqp4tm1.1Geno
Name: aquaporin 4; targeted mutation 1.1, Genoway
MGI ID: MGI:5297539
Synonyms: Aqp4flox
Gene: Aqp4  Location: Chr18:15389394-15403684 bp, - strand  Genetic Position: Chr18, 8.74 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:177412
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Generation of the conditional Aqp4tm1.1Geno allele
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aqp4 Mutation:  2 strains or lines available
References
Original:  J:177412 Haj-Yasein NN, et al., Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet. Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17815-20
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory