Tg(Plp1-cre)F633Rako
Transgene Detail

Summary

• Symbol: Tg(Plp1-cre)F633Rako
• Name: transgene insertion F633, Rashmi Kothary
• MGI ID: MGI:5297401
• Synonyms: Plp-Cre line F633
• Transgene: Tg(Plp1-cre)F633Rako Location: unknown
• Alliance: Tg(Plp1-cre)F633Rako page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Plp1-cre)F633Rako expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Plp1 (MGI:97623)

• Mutation details: Cre cDNA was inserted into a Plp1 promoter cassette consisting of exon 1 and intron 1 of the mouse Plp1 gene. The transgene construct was microinjected into 1-cell embryos. 6/29 founders were positive for the transgene and 2 showed successful germline transmission. RT-PCR indicated that Line F633 was expressed solely in the spinal cord, cerebellum, and cortex at P4 and P28. (J:172435)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Plp1 (mouse) Summary of all recombinase alleles driven by Plp1. Alliance mouse Plp1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:172435 Michalski JP, et al., The Proteolipid Protein Promoter Drives Expression outside of the Oligodendrocyte Lineage during Embryonic and Early Postnatal Development. PLoS One. 2011;6(5):e19772
• All: 1 reference(s)