Tg(Nr2e1-cre/ERT2)#Clzh
Transgene Detail

Summary

• Symbol: Tg(Nr2e1-cre/ERT2)#Clzh
• Name: transgene insertion, Chun-li Zhang
• MGI ID: MGI:5296897
• Synonyms: pTlx-CreER^T2
• Transgene: Tg(Nr2e1-cre/ERT2)#Clzh Location: unknown
• Alliance: Tg(Nr2e1-cre/ERT2)#Clzh page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Nr2e1-cre/ERT2)#Clzh expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nr2e1 (MGI:1100526)

• Mutation details: A cre/ERT2 sequence was inserted by homologous recombination into the first exon of the Nr2e1 (Tlx) locus in BAC clone RP24-344A4. The BAC was linearized and injected into pronuclei of fertilized oocytes. Twenty-three founders were obtained and screened for inducible cre activity by crossing to ROSA-EYFP reporter mice. No line numbers were provided for mouse lines used to generate the data. (J:176124)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nr2e1 (mouse) Summary of all recombinase alleles driven by Nr2e1. Alliance mouse Nr2e1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:176124 Niu W, et al., Activation of Postnatal Neural Stem Cells Requires Nuclear Receptor TLX. J Neurosci. 2011 Sep 28;31(39):13816-28
• All: 1 reference(s)