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Glis3tm1.2Chan
Targeted Allele Detail
Summary
Symbol: Glis3tm1.2Chan
Name: GLIS family zinc finger 3; targeted mutation 1.2, Lawrence Chan
MGI ID: MGI:5296613
Gene: Glis3  Location: Chr19:28236251-28657477 bp, - strand  Genetic Position: Chr19, 22.88 cM
Alliance: Glis3tm1.2Chan page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:177082
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Cre-mediated recombination removed exon 4. The absence of transript expression was confirmed. (J:177082)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Glis3 Mutation:  40 strains or lines available
References
Original:  J:177082 Yang Y, et al., The Kruppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice. Diabetologia. 2011 Oct;54(10):2595-605
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory