Sema6atm2e(EUCOMM)Hmgu
Targeted Allele Detail
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Symbol: |
Sema6atm2e(EUCOMM)Hmgu |
Name: |
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; targeted mutation 2e, Helmholtz Zentrum Muenchen GmbH |
MGI ID: |
MGI:5296576 |
Gene: |
Sema6a Location: Chr18:47378321-47504267 bp, - strand Genetic Position: Chr18, 25.08 cM, cytoband C
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Alliance: |
Sema6atm2e(EUCOMM)Hmgu page
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IMPC: |
Sema6a gene page |
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Mutant Cell Lines: |
HEPD0769_4_A05, HEPD0769_4_A07, HEPD0769_4_B06, HEPD0769_4_B08, HEPD0769_4_C05, HEPD0769_4_C07, HEPD0769_4_D06, HEPD0769_4_D07, HEPD0769_4_D08, HEPD0769_4_E07, HEPD0769_4_F05, HEPD0769_4_F06, HEPD0769_4_F07, HEPD0769_4_F08, HEPD0769_4_G05, HEPD0769_4_G07, HEPD0769_4_H06, HEPD0769_4_H08 |
Germline Transmission: |
Earliest citation of germline transmission:
J:188991
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Parent Cell Line: |
JM8A3.N1 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
Vector: L1L2_Pgk_P
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Mutation details: The L1L2_Pgk_P cassette was inserted at position 47425538 of Chromosome 18 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the PGK promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157065)
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Original: |
J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015; |
All: |
2 reference(s) |
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