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Tnip1tm1.2Pcoh
Targeted Allele Detail
Nomenclature
Symbol: Tnip1tm1.2Pcoh
Name: TNFAIP3 interacting protein 1; targeted mutation 1.2, Philip Cohen
MGI ID: MGI:5296230
Synonyms: ABIN1[D478-606]
Gene: Tnip1  Location: Chr11:54910787-54962917 bp, - strand  Genetic Position: Chr11, 32.13 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:176826
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsCre-mediated recombination removed the modified exon 14 through exon 16 resulting in the deletion of amino acids 478 through 606. (J:176826)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnip1 Mutation:  40 strains or lines available
References
Original:  J:176826 Nanda SK, et al., Polyubiquitin binding to ABIN1 is required to prevent autoimmunity. J Exp Med. 2011 Jun 6;208(6):1215-28
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/16/2017
MGI 6.09
The Jackson Laboratory