Gt(ROSA)26Sor^{tm1(CAG-flpe)Arte}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-flpe)Arte}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, TaconicArtemis
• MGI ID: MGI:5295849
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM

Mutation origin

• Germline Transmission: Unknown
• Parent Cell Line: ART4.12 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(CAG-flpe)Arte} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  chicken	CAG

• Mutation details: A contruct, which contained (5' to 3') a splice acceptor, translation initiation site, F3 site, zsgreen reporter, hygro cassette, CAGGS-flpe, and an FRT site, was inserted into the locus. This allele is a receptor for RMCE. (J:102771)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CAG (chicken) Summary of all recombinase alleles driven by CAG.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 942 strains or lines available

References

• Original: J:102771 Seibler J, et al., Single copy shRNA configuration for ubiquitous gene knockdown in mice. Nucleic Acids Res. 2005;33(7):e67
• All: 1 reference(s)