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Tg(Ins2-Nos2)Okam
Transgene Detail
Summary
Symbol: Tg(Ins2-Nos2)Okam
Name: transgene insertion, Hiroshi Okamoto
MGI ID: MGI:5295156
Synonyms: iNOS Tgm
Transgene: Tg(Ins2-Nos2)Okam  Location: unknown  
Alliance: Tg(Ins2-Nos2)Okam page
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ins2-Nos2)Okam expresses 1 gene
 
Mutation detailsThe transgenic construct was composed of the rat insulin II promoter and the 3.5 kb cDNA fragment containing the entire mouse Nos2 gene coding region with the SV40 intron/polyadenylation signal ligated to it. Lines 31 and 40 were subsequently established with expression only in the pancreatic islets. (J:45520)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:176735 Kishi S, et al., SOX9 protein induces a chondrogenic phenotype of mesangial cells and contributes to advanced diabetic nephropathy. J Biol Chem. 2011 Sep 16;286(37):32162-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory