About   Help   FAQ
Tet3tm1.2Gxu
Targeted Allele Detail
Nomenclature
Symbol: Tet3tm1.2Gxu
Name: tet methylcytosine dioxygenase 3; targeted mutation 1.2, Guo-Liang Xu
MGI ID: MGI:5294564
Synonyms: Tet3-
Gene: Tet3  Location: Chr6:83362373-83459084 bp, - strand  Genetic Position: Chr6, 35.94 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:176196
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 8 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 9 via homologous recombination. Flp and Cre mediated recombination removed the neo cassette and exons 8 and 9. (J:176196)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tet3 Mutation:  30 strains or lines available
References
Original:  J:176196 Gu TP, et al., The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature. 2011 Sep 29;477(7366):606-10
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/14/2017
MGI 6.11
The Jackson Laboratory