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Tet3tm1.2Gxu
Targeted Allele Detail
Nomenclature
Symbol: Tet3tm1.2Gxu
Name: tet methylcytosine dioxygenase 3; targeted mutation 1.2, Guo-Liang Xu
MGI ID: MGI:5294564
Synonyms: Tet3-
Gene: Tet3  Location: Chr6:83362373-83459084 bp, - strand  Genetic Position: Chr6, 35.94 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:176196
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 8 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 9 via homologous recombination. Flp and Cre mediated recombination removed the neo cassette and exons 8 and 9. (J:176196)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tet3 Mutation:  24 strains or lines available
References
Original:  J:176196 Gu TP, et al., The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature. 2011 Sep 29;477(7366):606-10
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory