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Gprc5btm1Yhir
Targeted Allele Detail
Nomenclature
Symbol: Gprc5btm1Yhir
Name: G protein-coupled receptor, family C, group 5, member B; targeted mutation 1, Yoshio Hirabayashi
MGI ID: MGI:5293387
Gene: Gprc5b  Location: Chr7:118972047-118995211 bp, - strand  Genetic Position: Chr7, 63.72 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:176063
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced with lacZ and neo cassettes via homologous recombination. LacZ expression recapitulates endogenous gene expression. (J:176063)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gprc5b Mutation:  21 strains or lines available
References
Original:  J:176063 Sano T, et al., Comparative characterization of GPRC5B and GPRC5CLacZ knockin mice; behavioral abnormalities in GPRC5B-deficient mice. Biochem Biophys Res Commun. 2011 Sep 2;412(3):460-5
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory