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Irf5tm1Ppr
Targeted Allele Detail
Nomenclature
Symbol: Irf5tm1Ppr
Name: interferon regulatory factor 5; targeted mutation 1, Paula Pitha-Rowe
MGI ID: MGI:5291913
Gene: Irf5  Location: Chr6:29526624-29541870 bp, + strand  Genetic Position: Chr6, 12.36 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:176418
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    LoxP sites were inserted to flank exon 2, which encodes part of the DNA binding site. (J:176418)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Irf5 Mutation:  22 strains or lines available
References
Original:  J:176418 Pitha-Rowe P, Creation of a conditional targeted mutation in interferon regulatory factor 5 (Irf5). MGI Direct Data Submission. 2011;
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/12/2021
MGI 6.17
The Jackson Laboratory