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Vldlrm1Btlr
Chemically induced Allele Detail
Nomenclature
Symbol: Vldlrm1Btlr
Name: very low density lipoprotein receptor; mutation 1, Bruce Beutler
MGI ID: MGI:5290092
Synonyms: r26
Gene: Vldlr  Location: Chr19:27216484-27254231 bp, + strand  Genetic Position: Chr19, 21.77 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU-induced C to T transition at position 27320144 bp of the genomic sequence of Vldlr, affecting nucleotide 2239 of the mRNA in exon 15 (NCBI RefSeq: (NM_013703.2), Variant 1; NM_001161420.1, variant 2). The mutation results in coding of a premature stop codon after amino acid 746 (R747*). (J:176337)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Vldlr Mutation:  5 strains or lines available
References
Original:  J:176337 Xia CH, et al., The role of Vldlr in intraretinal angiogenesis in mice. Invest Ophthalmol Vis Sci. 2011 Aug;52(9):6572-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/17/2015
MGI 5.21
The Jackson Laboratory