Tg(tetO-TAg*)175Kndl
Transgene Detail

Summary

• Symbol: Tg(tetO-TAg*)175Kndl
• Name: transgene insertion 175, Eric R Kandel
• MGI ID: MGI:5289793
• Transgene: Tg(tetO-TAg*)175Kndl Location: unknown
• Alliance: Tg(tetO-TAg*)175Kndl page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: A fragment encoding the C-terminal 86 amino acids of SV40 small t antigen (amino acids 88-174) that inhibits protein phosphatase 2A (PP2A) was fused in frame to a hemagglutinin (HA) epitope tag and placed under the control of a tetracycline operator (tetO) promoter. (J:135145)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:135145 Nicholls RE, et al., Transgenic mice lacking NMDAR-dependent LTD exhibit deficits in behavioral flexibility. Neuron. 2008 Apr 10;58(1):104-17
• All: 1 reference(s)