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Sox12tm1Vlf
Targeted Allele Detail
Summary
Symbol: Sox12tm1Vlf
Name: SRY (sex determining region Y)-box 12; targeted mutation 1, Veronique Lefebvre
MGI ID: MGI:5285295
Synonyms: Sox12flneo, Sox12tm2Weg
Gene: Sox12  Location: Chr2:152235531-152239966 bp, - strand  Genetic Position: Chr2, 74.94 cM
Alliance: Sox12tm1Vlf page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:175338
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of the coding region. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of the coding region. (J:175338)
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox12 Mutation:  8 strains or lines available
References
Original:  J:175338 Bhattaram P, et al., Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors. Nat Commun. 2010;1:9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory