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Targeted Allele Detail
Symbol: Cacng4tm1Ran
Name: calcium channel, voltage-dependent, gamma subunit 4; targeted mutation 1, Roger A Nicoll
MGI ID: MGI:5285084
Synonyms: gamma 4, Tarp gamma 4
Gene: Cacng4  Location: Chr11:107623183-107685383 bp, - strand  Genetic Position: Chr11, 70.29 cM, cytoband E1
Germline Transmission:  Earliest citation of germline transmission: J:175164
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 3 was replaced with a neomycin resistance cassette. Western blot analysis confirmed the absence of protein product. (J:175164)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cacng4 Mutation:  8 strains or lines available
Original:  J:175164 Milstein AD, et al., TARP subtypes differentially and dose-dependently control synaptic AMPA receptor gating. Neuron. 2007 Sep 20;55(6):905-18
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory