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Tg(Myh6-Mtpn)4Ssen
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-Mtpn)4Ssen
Name: transgene insertion 4, Subha Sen
MGI ID: MGI:5284885
Synonyms: Myo-Tg
Transgene: Tg(Myh6-Mtpn)4Ssen  Location: unknown  
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-Mtpn)4Ssen expresses 1 gene
 
Mutation detailsTransgene construct contains the mouse myotrophin (Mtpn) gene, under the direction of the mouse Myh6, myosin, heavy polypeptide 6, cardiac muscle, alpha, promoter. Four lines were generated (line 1, 2, 3, and 4). (J:89823)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:89823 Sarkar S, et al., Cardiac overexpression of myotrophin triggers myocardial hypertrophy and heart failure in transgenic mice. J Biol Chem. 2004 May 7;279(19):20422-34
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/05/2019
MGI 6.14
The Jackson Laboratory