About   Help   FAQ
Arhgef2Gt(IST13976A8)Tigm
Gene trapped Allele Detail
Nomenclature
Symbol: Arhgef2Gt(IST13976A8)Tigm
Name: rho/rac guanine nucleotide exchange factor (GEF) 2; gene trap IST13976A8, Texas A&M Institute for Genomic Medicine
MGI ID: MGI:5200558
Gene: Arhgef2  Location: Chr3:88605966-88648052 bp, + strand  Genetic Position: Chr3, 38.9 cM, cytoband F1
Mutation
origin
Mutant Cell Line:  IST13976A8
Germline Transmission:  Earliest citation of germline transmission: J:209086
Parent Cell Line:  Lex3.13 (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Gene trapped (Null/knockout)
Mutation:    Insertion of gene trap vector
 
Mutation detailsThe gene trap vector inserted between exon 4 and 5. Western blot analysis confirmed the absence of protein expression in macrophages. (J:209086)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Mice Carrying this Mutation: 31 assay results
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Arhgef2 Mutation:  25 strains or lines available
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/11/2020
MGI 6.14
The Jackson Laboratory