Mthfd1^{Gt(IST13390B6)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Mthfd1^{Gt(IST13390B6)Tigm}
• Name: methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase; gene trap IST13390B6, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:5170760
• Gene: Mthfd1 Location: Chr12:76302072-76366577 bp, + strand Genetic Position: Chr12, 33.52 cM, cytoband D2

Mutation origin

• Mutant Cell Line: IST13390B6
• Germline Transmission: Unknown
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped
• Mutation: Insertion of gene trap vector
• Trapped gene association determined by genome coordinate overlap and strand.
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST13390B6HMF1	JM225817 ; (MGI Seq Detail)	inverse PCR	Chr12:76307824-76308194 bp (+)
  IST13390B6BBF1	JM225816 ; (MGI Seq Detail)	inverse PCR	Chr12:76308116-76308194 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  55 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Mthfd1 Mutation: 80 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)