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Arhgap15tm1Ehi
Targeted Allele Detail
Nomenclature
Symbol: Arhgap15tm1Ehi
Name: Rho GTPase activating protein 15; targeted mutation 1, Emilio Hirsch
MGI ID: MGI:5142283
Gene: Arhgap15  Location: Chr2:43748824-44395953 bp, + strand  Genetic Position: Chr2, 26.13 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174896
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsThe gene was disrupted by insertion of a lacZ and a neomycin resistance cassette in the ATG start site in exon 1. (J:174896)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 63 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arhgap15 Mutation:  19 strains or lines available
References
Original:  J:174896 Costa C, et al., The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions. Blood. 2011 Jul 28;118(4):1099-108
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/10/2020
MGI 6.16
The Jackson Laboratory