Crtac1^tm1Kota
Targeted Allele Detail

Summary

• Symbol: Crtac1^tm1Kota
• Name: cartilage acidic protein 1; targeted mutation 1, Kohtaro Takei
• MGI ID: MGI:5141316
• Gene: Crtac1 Location: Chr19:42271474-42421405 bp, - strand Genetic Position: Chr19, 36.07 cM
• Alliance: Crtac1^tm1Kota page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174418
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a floxed neo cassette via homologous recombination. Immunohistochemical analysis confirmed the absence of protein expression in E14 brains from homozygous mice. (J:174418)

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Crtac1 Mutation: 41 strains or lines available

References

• Original: J:174418 Sato Y, et al., Cartilage acidic protein-1B (LOTUS), an endogenous Nogo receptor antagonist for axon tract formation. Science. 2011 Aug 5;333(6043):769-73
• All: 9 reference(s)