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Crtac1tm1Kota
Targeted Allele Detail
Nomenclature
Symbol: Crtac1tm1Kota
Name: cartilage acidic protein 1; targeted mutation 1, Kohtaro Takei
MGI ID: MGI:5141316
Gene: Crtac1  Location: Chr19:42283037-42431783 bp, - strand  Genetic Position: Chr19, 36.07 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174418
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a floxed neo cassette via homologous recombination. Immunohistochemical analysis confirmed the absence of protein expression in E14 brains from homozygous mice. (J:174418)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Crtac1 Mutation:  22 strains or lines available
References
Original:  J:174418 Sato Y, et al., Cartilage acidic protein-1B (LOTUS), an endogenous Nogo receptor antagonist for axon tract formation. Science. 2011 Aug 5;333(6043):769-73
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory