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Col12a1tm1Debi
Targeted Allele Detail
Nomenclature
Symbol: Col12a1tm1Debi
Name: collagen, type XII, alpha 1; targeted mutation 1, David Birk
MGI ID: MGI:5141135
Gene: Col12a1  Location: Chr9:79598991-79718831 bp, - strand  Genetic Position: Chr9, 43.82 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174217
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 through exon 5 were replaced with a floxed PGK-neo selection cassette. Immunoblot analysis indicated that type XII collagen expression was completely absent. (J:174217)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col12a1 Mutation:  97 strains or lines available
References
Original:  J:174217 Izu Y, et al., Type XII collagen regulates osteoblast polarity and communication during bone formation. J Cell Biol. 2011 Jun 13;193(6):1115-30
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory