Cd1d1^tm2Aben
Targeted Allele Detail

Summary

• Symbol: Cd1d1^tm2Aben
• Name: CD1d1 antigen; targeted mutation 2, Albert Bendelac
• MGI ID: MGI:5056289
• Synonyms: CDI-TD
• Gene: Cd1d1 Location: Chr3:86903141-86906748 bp, - strand Genetic Position: Chr3, 37.91 cM
• Alliance: Cd1d1^tm2Aben page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174337
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted
• Mutations: Insertion, Intragenic deletion
• Mutation details: The nucleotides encoding the SAYQDIR carboxy-terminus (cytoplasmic tail) segment were deleted. A floxed neo cassette was inserted downstream of the last exon. (J:174337)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cd1d1 Mutation: 30 strains or lines available

References

• Original: J:174337 Chiu YH, et al., Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d. Nat Immunol. 2002 Jan;3(1):55-60
• All: 5 reference(s)