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Cd1d1tm2Aben
Targeted Allele Detail
Nomenclature
Symbol: Cd1d1tm2Aben
Name: CD1d1 antigen; targeted mutation 2, Albert Bendelac
MGI ID: MGI:5056289
Synonyms: CDI-TD
Gene: Cd1d1  Location: Chr3:86995834-86999441 bp, - strand  Genetic Position: Chr3, 37.91 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174337
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe nucleotides encoding the SAYQDIR carboxy-terminus (cytoplasmic tail) segment were deleted. A floxed neo cassette was inserted downstream of the last exon. (J:174337)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd1d1 Mutation:  8 strains or lines available
References
Original:  J:174337 Chiu YH, et al., Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d. Nat Immunol. 2002 Jan;3(1):55-60
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory