Siglec15^tm1.2Cfg
Targeted Allele Detail

Summary

• Symbol: Siglec15^tm1.2Cfg
• Name: sialic acid binding Ig-like lectin 15; targeted mutation 1.2, Consortium for Functional Glycomics
• MGI ID: MGI:5052359
• Gene: Siglec15 Location: Chr18:78086829-78100610 bp, - strand Genetic Position: Chr18, 52.43 cM
• Alliance: Siglec15^tm1.2Cfg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and a loxP-flanked neomycin and thymidine kinase selection cassette was inserted downstream of exon 5. Cre-mediated recombination removed the neomycin cassette. Exons 2 through 5 were subsequently removed from properly targeted mice by crossing to transgenic mice carrying Hprt^{tm1(CMV-cre)Brd}. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Siglec15 Mutation: 25 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 2 reference(s)