Mgl2/Clec10a^tm1.1Cfg
Targeted Allele Detail

Summary

• Symbol: Mgl2/Clec10a^tm1.1Cfg
• Name: macrophage galactose N-acetyl-galactosamine specific lectin 2; targeted mutation 1.1, Consortium for Functional Glycomics
• MGI ID: MGI:5052341
• Gene: Mgl2 Location: Chr11:70021155-70028376 bp, + strand Genetic Position: Chr11, 42.99 cM
• Alliance: Mgl2/Clec10a^tm1.1Cfg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion
• Mutation details: An FRT-flanked selection vector containing a neomycin resistance gene and a single 5' loxP site was inserted upstream of exon 2 of the Mgl2 gene and a second loxP site was inserted downstream of exon 10 of the Clec10a gene. The selection cassette and exons 2 through 10 of Mgl2 and all of the Clec10a gene were subsequently removed from properly targeted mice by crossing to transgenic mice carrying Tg(EIIa-cre)C5379Lmgd. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mgl2 Mutation: 25 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 2 reference(s)