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Gpr119tm1Jleo
Targeted Allele Detail
Nomenclature
Symbol: Gpr119tm1Jleo
Name: G-protein coupled receptor 119; targeted mutation 1, James Leonard
MGI ID: MGI:5051634
Gene: Gpr119  Location: ChrX:48667979-48674478 bp, - strand  Genetic Position: ChrX, 25.69 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174048
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced the coding portion of the gene. RT-PCR and immunofluorescence analysis indicated that both mRNA and protein product are absent. (J:174048)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpr119 Mutation:  3 strains or lines available
References
Original:  J:174048 Chu ZL, et al., A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release. Endocrinology. 2007 Jun;148(6):2601-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/17/2018
MGI 6.11
The Jackson Laboratory