Sirt6^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Sirt6^{tm1(KOMP)Vlcg}
• Name: sirtuin 6; targeted mutation 1, Velocigene
• MGI ID: MGI:5051305
• Gene: Sirt6 Location: Chr10:81457621-81463631 bp, - strand Genetic Position: Chr10, 39.72 cM
• IMPC: Sirt6 gene page

Mutation origin

• Mutant Cell Lines: 17425A-A4, 17425A-A8, 17425A-C3, 17425A-D6, 17425A-D9, 17425A-H1
• Germline Transmission: Unknown
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 5224bp between positions 81458145-81463368 of Chromosome 10 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Sirt6 Mutation: 39 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 1 reference(s)