Timp3^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Timp3^{tm1(KOMP)Vlcg}
• Name: tissue inhibitor of metalloproteinase 3; targeted mutation 1, Velocigene
• MGI ID: MGI:5051171
• Gene: Timp3 Location: Chr10:86136276-86185369 bp, + strand Genetic Position: Chr10, 42.83 cM, cytoband C1-D1
• Alliance: Timp3^{tm1(KOMP)Vlcg} page
• IMPC: Timp3 gene page

Mutation origin

• Mutant Cell Lines: 17200A-D2, 17200A-E2, 17200A-E3, 17200A-G11, 17200A-G12
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 37594bp between positions 86136721-86174314 of Chromosome 10 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Timp3 Mutation: 18 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)