Dnajb6^{tm3(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Dnajb6^{tm3(EUCOMM)Wtsi}
• Name: DnaJ heat shock protein family (Hsp40) member B6; targeted mutation 3, Wellcome Trust Sanger Institute
• MGI ID: MGI:5050917
• Gene: Dnajb6 Location: Chr5:29940896-29991476 bp, + strand Genetic Position: Chr5, 15.27 cM, cytoband B1
• IMPC: Dnajb6 gene page

Mutation origin

• Mutant Cell Lines: EPD0566_1_A09, EPD0566_1_A10, EPD0566_1_A11, EPD0566_1_A12, EPD0566_1_B09, EPD0566_1_B10, EPD0566_1_B12, EPD0566_1_C10, EPD0566_1_C12, EPD0566_1_D09, EPD0566_1_D11, EPD0566_1_E09, EPD0566_1_E10, EPD0566_1_E11, EPD0566_1_F09, EPD0566_1_F10, EPD0566_1_F11, EPD0566_1_F12, EPD0566_1_G09, EPD0566_1_G10, EPD0566_1_G12, EPD0566_1_H09, EPD0566_1_H10
• Germline Transmission: Unknown
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 5358 starting at position 29953319 and ending at position 29958677 of Chromosome 5 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:155845, J:173534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnajb6 Mutation: 72 strains or lines available

References

• Original: J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010
• All: 2 reference(s)