Tg(Krt5-Ctnnb1*)#Gluk
Transgene Detail

Summary

• Symbol: Tg(Krt5-Ctnnb1*)#Gluk
• Name: transgene insertion, Marina A Glukhova
• MGI ID: MGI:5049918
• Synonyms: K5-deltaN57-betacat
• Transgene: Tg(Krt5-Ctnnb1*)#Gluk Location: unknown
• Alliance: Tg(Krt5-Ctnnb1*)#Gluk page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Krt5-Ctnnb1*)#Gluk expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ctnnb1 (MGI:88276)

• Mutation details: A modified mouse beta-catenin that lacks sequence for amino acids 1-57 was hemagglutinin tagged and placed under the control of the keratin 5 promoter. Two transgenic lines (7, and 33) are discussed. Between 10 and 20 copies of the transgene were inserted. (J:95360)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:95360 Teuliere J, et al., Targeted activation of {beta}-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia. Development. 2005 Jan;132(2):267-277
• All: 4 reference(s)