About   Help   FAQ
Abcc10tm1Eah
Targeted Allele Detail
Nomenclature
Symbol: Abcc10tm1Eah
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 10; targeted mutation 1, Elizabeth A Hopper-Borge
MGI ID: MGI:5013608
Gene: Abcc10  Location: Chr17:46303221-46328352 bp, - strand  Genetic Position: Chr17, 22.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:172648
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 4 through 6 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on kidney cell lines and spleen extracts. (J:172648)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Abcc10 Mutation:  26 strains or lines available
References
Original:  J:172648 Hopper-Borge EA, et al., Contribution of Abcc10 (Mrp7) to In Vivo Paclitaxel Resistance as Assessed in Abcc10-/- Mice. Cancer Res. 2011 May 15;71(10):3649-3657
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory