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Clec16acurt
Spontaneous Allele Detail
Nomenclature
Symbol: Clec16acurt
Name: C-type lectin domain family 16, member A; curvy tail
MGI ID: MGI:5009280
Gene: Clec16a  Location: Chr16:10545339-10744878 bp, + strand  Genetic Position: Chr16, 5.68 cM
Mutation
origin
Strain of Origin:  SWR/J-Clcn1adr-mto/J
Mutation
description
Allele Type:    Spontaneous
Mutation:    Intragenic deletion
 
Mutation detailsThis spontaneous mutation presents as a 4 base pair deletion in exon 21 at chromosome 16 position 10,694,632-635 bp (GRCm38), which results in a frameshift mutation that leads to the introduction of novel amino acids and an early termination codon. Transcript levels of this mutant allele were found to be significantly decreased in homozygous embryonic fibroblasts. (J:190968, J:222308, J:251104)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Clec16a Mutation:  5 strains or lines available
References
Original:  J:172931 Harris BS, et al., Curvy tail: a new skeletal mutation that maps to Chromosome 16. MGI Direct Data Submission. 2011;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory