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Targeted Allele Detail
Symbol: Gjd4tm1.1Malt
Name: gap junction protein, delta 4; targeted mutation 1.1, Julia von Maltzahn
MGI ID: MGI:5009133
Gene: Gjd4  Location: Chr18:9278607-9282809 bp, - strand  Genetic Position: Chr18, 4.91 cM
Germline Transmission:  Earliest citation of germline transmission: J:172698
Parent Cell Line:  H1 (ES Cell)
Strain of Origin:  129S2/SvPas
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe coding region was replaced with an EGFP and FRT-flanked neo cassette. Flp-mediated recombination removed the neo cassette. Immunohistochemistry confirmed the absence of protein expression in intercostal muscles of E13.5 muscles. (J:172698)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gjd4 Mutation:  17 strains or lines available
Original:  J:172698 von Maltzahn J, et al., Connexin39 deficient mice display accelerated myogenesis and regeneration of skeletal muscle. Exp Cell Res. 2011 May 1;317(8):1169-78
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory