Nudt17^tm2(KOMP)Mbp
Targeted Allele Detail

Summary

• Symbol: Nudt17^tm2(KOMP)Mbp
• Name: nudix hydrolase 17; targeted mutation 2, Mouse Biology Program, UC Davis
• MGI ID: MGI:5007946
• Gene: Nudt17 Location: Chr3:96613383-96615878 bp, - strand Genetic Position: Chr3, 41.95 cM, cytoband F2
• IMPC: Nudt17 gene page

Mutation origin

• Mutant Cell Lines: DEPD00558_3_A09, DEPD00558_3_A10, DEPD00558_3_A11, DEPD00558_3_B09, DEPD00558_3_B10, DEPD00558_3_B11, DEPD00558_3_B12, DEPD00558_3_C09, DEPD00558_3_C10, DEPD00558_3_C11, DEPD00558_3_C12, DEPD00558_3_D09, DEPD00558_3_D10, DEPD00558_3_D11, DEPD00558_3_D12, DEPD00558_3_E09, DEPD00558_3_E10, DEPD00558_3_E11, DEPD00558_3_E12, DEPD00558_3_F09, DEPD00558_3_F10, DEPD00558_3_F11, DEPD00558_3_F12, DEPD00558_3_G09, DEPD00558_3_G10, DEPD00558_3_G11, DEPD00558_3_G12, DEPD00558_3_H09, DEPD00558_3_H10
• Germline Transmission: Unknown
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: L1L2_Bact_P
• Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 1464 starting at position 96614116 and ending at position 96615580 of Chromosome 3 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml (J:157064)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nudt17 Mutation: 6 strains or lines available

References

• Original: J:157064 University of California, Davis, Alleles produced for the KOMP project by the University of California, Davis. MGI Direct Data Submission. 2010
• All: 1 reference(s)