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Slc29a3tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Slc29a3tm1Lex
Name: solute carrier family 29 (nucleoside transporters), member 3; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID: MGI:5007332
Gene: Slc29a3  Location: Chr10:60712072-60752794 bp, - strand  Genetic Position: Chr10, 31.38 cM, cytoband B4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171883
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 and 2 were replaced with a beta-geo/Puro cassette. Western blot analysis confirmed the absence of protein expression in bone marrow-derived macrophages. (J:171883)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Slc29a3 Mutation:  2 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory