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Nbeal2tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Nbeal2tm1Lex
Name: neurobeachin-like 2; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID: MGI:5007262
Gene: Nbeal2  Location: Chr9:110624789-110654161 bp, - strand  Genetic Position: Chr9, 60.27 cM
Impaired wound healing in Nbeal2tm1Lex/Nbeal2tm1Lex mice

Show the 6 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171883
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExons 4 through 11 of the coding region were targeted by homologous recombination. RT-PCR confirmed absence of mRNA in different tissues. (J:171883, J:201413)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nbeal2 Mutation:  54 strains or lines available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2018
MGI 6.12
The Jackson Laboratory