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Acp1tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Acp1tm1Lex
Name: acid phosphatase 1, soluble; targeted mutation 1, Lexicon Pharmaceuticals
MGI ID: MGI:5007006
Gene: Acp1  Location: Chr12:30893326-30911589 bp, - strand  Genetic Position: Chr12, 13.0 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171883
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe Acp1 gene consists of 5 exons, with the start codon located in exon 1 (NCBI accession AK053903). Exons 1 through 3 were targeted by homologous recombination. Disruption of the target gene was confirmed by Southern hybridization analysis. (J:171883)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Acp1 Mutation:  1 strain or line available
Notes
See also, data as provided by Lexicon Genetics, Inc.
References
Original:  J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory