Gt(ROSA)26Sor^{tm4.1(CAG-lacZ)Dym}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm4.1(CAG-lacZ)Dym}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4.1, Susan M Dymecki
• MGI ID: MGI:5006934
• Synonyms: RC::Fa
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm4.1(CAG-lacZ)Dym} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136096
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: Germ-line cre deletion of the loxP-flanked EGFP cassette generated this Flp only-responsive reporter allele. In presence of Flp (or Flpe), the Frt-flanked PGK-Neo stop cassette is excised allowing expression of lacZ in Flp-expression progenitor cells.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1061 strains or lines available

References

• Original: J:136096 Jensen P, et al., Redefining the serotonergic system by genetic lineage. Nat Neurosci. 2008 Apr;11(4):417-9
• All: 3 reference(s)