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Targeted Allele Detail
Symbol: Wnt4tm1.2Bhr
Name: wingless-type MMTV integration site family, member 4; targeted mutation 1.2, Richard R Behringer
MGI ID: MGI:5006677
Synonyms: Wnt4del
Gene: Wnt4  Location: Chr4:137277489-137299726 bp, + strand  Genetic Position: Chr4, 69.8 cM
Germline Transmission:  Earliest citation of germline transmission: J:171430
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of exon 2 and a loxP site and an FRT flanked neo cassette were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. Cre mediated recombination removed exon 2. (J:171430)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wnt4 Mutation:  12 strains or lines available
Original:  J:171430 Kobayashi A, et al., {beta}-Catenin is essential for Mullerian duct regression during male sexual differentiation. Development. 2011 May;138(10):1967-75
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory