Rspo2^tm1.1Jky
Targeted Allele Detail

Summary

• Symbol: Rspo2^tm1.1Jky
• Name: R-spondin 2; targeted mutation 1.1, Jeong Yoon
• MGI ID: MGI:5004905
• Synonyms: Rspo2^deltaZN
• Gene: Rspo2 Location: Chr15:42884190-43034222 bp, - strand Genetic Position: Chr15, 16.73 cM
• Alliance: Rspo2^tm1.1Jky page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171482
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 was replaced with an FRT-flanked IRES, lacZ, and neo cassette. Flp-mediated recombination removed the reporter and selection cassette. (J:171482)

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rspo2 Mutation: 19 strains or lines available

References

• Original: J:171482 Jin YR, et al., The canonical Wnt signaling activator, R-spondin2, regulates craniofacial patterning and morphogenesis within the branchial arch through ectodermal-mesenchymal interaction. Dev Biol. 2011 Apr 1;352(1):1-13
• All: 2 reference(s)