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Transgene Detail
Symbol: Tg(Myh6-TRPC3*)6.6Jmol
Name: transgene insertion 6.6, Jeffery Molkentin
MGI ID: MGI:5002483
Synonyms: dnTRPC3
Transgene: Tg(Myh6-TRPC3*)6.6Jmol  Location: unknown  
Strain of Origin:  FVB
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
Tg(Myh6-TRPC3*)6.6Jmol expresses 1 gene
Mutation detailsThe dnTRPC3 transgene contains amino acids 1-302 of the human transient receptor potential cation channel, subfamily C, member 3 (TRPC3) under the control of the mouse myosin, heavy polypeptide 6, cardiac muscle, alpha (Myh6) promoter. Line 6.6 was generated. (J:159297)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:159297 Wu X, et al., TRPC channels are necessary mediators of pathologic cardiac hypertrophy. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7000-5
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
The Jackson Laboratory