Gt(ROSA)26Sortm2(Pik3ca)Egan
Targeted Allele Detail
|
Symbol: |
Gt(ROSA)26Sortm2(Pik3ca)Egan |
Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Sean E Egan |
MGI ID: |
MGI:5000473 |
Synonyms: |
R26-Pik3cawt, R26StopFL-Pik3ca |
Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
|
Alliance: |
Gt(ROSA)26Sortm2(Pik3ca)Egan page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:170898
|
Parent Cell Line: |
W4 (ES Cell)
|
Strain of Origin: |
129S6/SvEvTac
|
|
Allele Type: |
|
Targeted (Conditional ready, Inserted expressed sequence) |
Mutation: |
|
Insertion
|
|
|
Gt(ROSA)26Sortm2(Pik3ca)Egan expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Note |
mouse |
Pik3ca (MGI:1206581) |
|
|
|
|
Mutation details: The following sequences were inserted into intron 1: splice acceptor site, a STOP cassette (loxP site flanked neomycin resistance gene cassette), Pik3ca cDNA sequence, and bovine GH poly(A) signal sequences.
(J:170898)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Gt(ROSA)26Sor Mutation: |
942 strains or lines available
|
|
Original: |
J:170898 Adams JR, et al., Cooperation between Pik3ca and p53 Mutations in Mouse Mammary Tumor Formation. Cancer Res. 2011 Apr 1;71(7):2706-2717 |
All: |
2 reference(s) |
|