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Trib1tm1Aki
Targeted Allele Detail
Nomenclature
Symbol: Trib1tm1Aki
Name: tribbles pseudokinase 1; targeted mutation 1, Shizuo Akira
MGI ID: MGI:5000311
Gene: Trib1  Location: Chr15:59648350-59656550 bp, + strand  Genetic Position: Chr15, 25.41 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:126085
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe second coding exon was replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on macrophage extracts. (J:126085)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trib1 Mutation:  8 strains or lines available
References
Original:  J:126085 Yamamoto M, et al., Enhanced TLR-mediated NF-IL6 dependent gene expression by Trib1 deficiency. J Exp Med. 2007 Sep 3;204(9):2233-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory