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Tg(IVL-cre/ERT2)1Blpn
Transgene Detail
Nomenclature
Symbol: Tg(IVL-cre/ERT2)1Blpn
Name: transgene insertion 1, Cedric Blanpain
MGI ID: MGI:4999984
Synonyms: InvCREER, INV-CreERT2
Transgene: Tg(IVL-cre/ERT2)1Blpn  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsA cre/ERT2 fragment was cloned into a vector containing the human involucrin (IVL) promoter, the SV40 intron, and the SV40 polyA signal. The transgenic construct was microinjected into fertilized oocytes, and three founders were generated. Expression profiles were screened with crosses to ROSA-YFP reporter mice. (J:172048)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: IVL     Summary of all recombinase alleles driven by IVL.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:172048 Lapouge G, et al., Identifying the cellular origin of squamous skin tumors. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7431-6
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory