Creb1tm3.1Gsc
Targeted Allele Detail
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Symbol: |
Creb1tm3.1Gsc |
Name: |
cAMP responsive element binding protein 1; targeted mutation 3.1, Gunther Schutz |
MGI ID: |
MGI:4999627 |
Synonyms: |
Creb1- |
Gene: |
Creb1 Location: Chr1:64571963-64643707 bp, + strand Genetic Position: Chr1, 32.74 cM, cytoband C1/C5
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Alliance: |
Creb1tm3.1Gsc page
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Lung development abnormalities in Creb1tm3.1Gsc/Creb1tm3.1Gsc mice
Show the 3 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:171712
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Parent Cell Line: |
E14.1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A single loxP site was inserted 5' to exon 10 and a loxP flanked neomycin and thymidine kinase cassette was inserted 3' to exon 10. Cre mediated recombination removed the selection cassette and exon 10.
(J:76211, J:171712)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Creb1 Mutation: |
59 strains or lines available
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Original: |
J:171712 Bird AD, et al., cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development. PLoS One. 2011;6(3):e17843 |
All: |
3 reference(s) |
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